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High-mobility group : ウィキペディア英語版 | High-mobility group High-Mobility Group or HMG is a group of chromosomal proteins that are involved in the regulation of DNA-dependent processes such as transcription, replication, recombination, and DNA repair. ==Families== The HMG proteins are subdivided into 3 superfamilies each containing a characteristic functional domain: * HMGA – contains an AT-hook domain * * HMGA1 * * HMGA2 * HMGB – contains a HMG-box domain * * HMGB1 * * HMGB2 * * HMGB3 * * HMGB4 * HMGN – contains a nucleosomal binding domain * * HMGN1 * * HMGN2 * * HMGN3 * * HMGN4 * Sex-Determining Region Y Protein * TCF Transcription Factors * * Lymphoid enhancer-binding factor 1 * * T Cell Transcription Factor 1 Proteins containing any of these embedded in their sequence are known as HMG motif proteins. HMG-box proteins are found in a variety of eukaryotic organisms. They were originally isolated from mammalian cells, and named according to their electrophoretic mobility in polyacrylamide gels.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「High-mobility group」の詳細全文を読む
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